Granulomatous Meningoencephalitis and Necrotizing Encephalitis

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Filed Under: Neurology


Granulomatous meningoencephalitis (GME) and necrotizing encephalitis (NE) are disorders that arise from inflammation of the brai and/or spinal cord and their coverings (the meninges).  These diseases affect predominately young, small-breed dogs.

Causes:  Both GME and NE are presently considered to be autoimmune disorders, meaning that the body launches an abnormal attack against its own nervous system tissues.  Potential triggers for the autoimmune attack may include infections and vaccinations.  Genetics may also play a role in the development of GME and NE.

Although any breed of dog may be affected with GME, toy breeds are affected most often.  Breeds commonly affected by NE include the pug, Maltese, Yorkshire terrier, Chihuahua, French bulldog, shih tzu, and Pomerainian.  (More informaiton in below attachment...)